Hi Anej,
So this is a very interesting issue and could be for a variety of reasons. My first guess would be maybe your out of date version of Creo 2.0 is conflicting with the most current version of the mouse drivers.
The newest version can be downloaded here: https://www.ptc.com/appserver/auth/it/esd/academicFree.jsp
If that still doesn't work then maybe contacting the support team at 3DConnexion could shed more light on the problem.
Sorry I don't have a quick answer for you! Let me know if you figure somethign out.
Thanks